Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_A0705Phosphoglycerate transport regulatory protein PgtB, putative; Similar to PID:858753; identified by sequence similarity; putative. (789 aa)    
Predicted Functional Partners:
VC_A0704
Phosphoglycerate transport system transcriptional regulatory protein PgtA; Similar to GB:M13923 SP:P06184 PID:154255; identified by sequence similarity; putative.
 
  
 0.996
VC_A0706
Phosphoglycerate transport regulatory protein PgtC, putative; Similar to GB:M21279 SP:P37591 GB:X52093 PID:154258; identified by sequence similarity; putative.
 
 
 0.986
cqsS
Sensor histidine kinase/response regulator LuxN; Senses the quorum-sensing autoinducer CAI-1 ((S)-3- hydroxytridecan-4-one) which probably functions as an intragenus signal. The sensory signal is then relayed to LuxU and LuxO.
  
     0.746
VC_1050
Response regulator; Similar to SP:P37055 GB:M64675 GB:X66003 PID:41734 GB:U00096; identified by sequence similarity; putative.
  
     0.742
VC_1319
Sensor histidine kinase; Similar to GB:M36795 SP:P08336 GB:X13307 PID:145590 PID:305015; identified by sequence similarity; putative.
  
     0.723
luxQ
Sensor histidine kinase LuxQ; At low cell density, in absence of AI-2 (autoinducer 2), LuxQ has a kinase activity and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to LuxU, and ultimately to LuxO. At high cell density, in the presence of AI-2, the kinase activity is inactivated, and the response regulator domain has a phosphatase activity (By similarity).
  
     0.662
VC_1398
Chemotaxis protein CheY; Similar to PID:2292999; identified by sequence similarity; putative.
  
     0.632
VC_A0707
Regulatory protein UhpC, putative; Similar to GB:M89480 SP:P27669 GB:X52093 PID:154410; identified by sequence similarity; putative.
 
   
 0.599
VC_A1114
ParB family protein; Similar to SP:P08867 GB:M12987 GB:X04619 PID:148592 PID:42432; identified by sequence similarity; putative; Belongs to the ParB family.
  
     0.581
VC_A1096
Chemotaxis protein CheY; Similar to GB:U13166 PID:534836; identified by sequence similarity; putative.
  
     0.574
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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