STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_A0705Phosphoglycerate transport regulatory protein PgtB, putative; Similar to PID:858753; identified by sequence similarity; putative. (789 aa)    
Predicted Functional Partners:
VC_A0704
Phosphoglycerate transport system transcriptional regulatory protein PgtA; Similar to GB:M13923 SP:P06184 PID:154255; identified by sequence similarity; putative.
 
  
 0.978
VC_A0706
Phosphoglycerate transport regulatory protein PgtC, putative; Similar to GB:M21279 SP:P37591 GB:X52093 PID:154258; identified by sequence similarity; putative.
 
  
 0.919
VC_1602
Chemotaxis protein CheV; Similar to SP:P37599 GB:U05345 GB:Z29584 PID:453378 PID:580837; identified by sequence similarity; putative.
  
  
  0.813
cqsS
Sensor histidine kinase/response regulator LuxN; Senses the quorum-sensing autoinducer CAI-1 ((S)-3- hydroxytridecan-4-one) which probably functions as an intragenus signal. The sensory signal is then relayed to LuxU and LuxO.
  
  
  0.811
VC_1050
Response regulator; Similar to SP:P37055 GB:M64675 GB:X66003 PID:41734 GB:U00096; identified by sequence similarity; putative.
  
  
  0.808
luxQ
Sensor histidine kinase LuxQ; At low cell density, in absence of AI-2 (autoinducer 2), LuxQ has a kinase activity and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to LuxU, and ultimately to LuxO. At high cell density, in the presence of AI-2, the kinase activity is inactivated, and the response regulator domain has a phosphatase activity (By similarity).
  
  
  0.749
VC_1319
Sensor histidine kinase; Similar to GB:M36795 SP:P08336 GB:X13307 PID:145590 PID:305015; identified by sequence similarity; putative.
  
     0.723
VC_2369
Sensor histidine kinase FexB; Similar to SP:P22763 GB:X53315 PID:40951 PID:606149 GB:U00096; identified by sequence similarity; putative.
  
  
  0.686
VC_A1096
Chemotaxis protein CheY; Similar to GB:U13166 PID:534836; identified by sequence similarity; putative.
  
  
  0.684
VC_1398
Chemotaxis protein CheY; Similar to PID:2292999; identified by sequence similarity; putative.
  
  
  0.660
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.