| node1 | node2 | node1 annotation | node2 annotation | score |
| VC_1538 | VC_A0802 | Hypothetical protein; Identified by Glimmer2; putative. | Conserved hypothetical protein; Identified by Glimmer2; putative. | 0.426 |
| VC_A0536 | VC_A0681 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Conserved hypothetical protein; Phosphodiesterase (PDE) that catalyzes the hydrolysis of 3'3'-cyclic GMP-AMP (3'3'-cGAMP), leading to linear 5'-pApG. Also displays 5'-nucleotidase activity, further hydrolyzing 5'-pApG to 5'-ApG. Counteracts the function of the 3'3'-cGAMP synthase DncV, and is involved in the modulation of intracellular 3'3'-cGAMP levels. Enhances bacterial chemotaxis and inhibits intestinal colonization in vivo. Thus exerts a crucial role in regulating bacterial infectivity through catalyzing 3'3'-cGAMP degradation. Is specific for 3'3'-cGAMP since it cannot degrade ot [...] | 0.679 |
| VC_A0536 | VC_A0802 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Conserved hypothetical protein; Identified by Glimmer2; putative. | 0.542 |
| VC_A0536 | VC_A1083 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Conserved hypothetical protein; Identified by Glimmer2; putative. | 0.895 |
| VC_A0681 | VC_A0536 | Conserved hypothetical protein; Phosphodiesterase (PDE) that catalyzes the hydrolysis of 3'3'-cyclic GMP-AMP (3'3'-cGAMP), leading to linear 5'-pApG. Also displays 5'-nucleotidase activity, further hydrolyzing 5'-pApG to 5'-ApG. Counteracts the function of the 3'3'-cGAMP synthase DncV, and is involved in the modulation of intracellular 3'3'-cGAMP levels. Enhances bacterial chemotaxis and inhibits intestinal colonization in vivo. Thus exerts a crucial role in regulating bacterial infectivity through catalyzing 3'3'-cGAMP degradation. Is specific for 3'3'-cGAMP since it cannot degrade ot [...] | Conserved hypothetical protein; Identified by Glimmer2; putative. | 0.679 |
| VC_A0681 | VC_A0802 | Conserved hypothetical protein; Phosphodiesterase (PDE) that catalyzes the hydrolysis of 3'3'-cyclic GMP-AMP (3'3'-cGAMP), leading to linear 5'-pApG. Also displays 5'-nucleotidase activity, further hydrolyzing 5'-pApG to 5'-ApG. Counteracts the function of the 3'3'-cGAMP synthase DncV, and is involved in the modulation of intracellular 3'3'-cGAMP levels. Enhances bacterial chemotaxis and inhibits intestinal colonization in vivo. Thus exerts a crucial role in regulating bacterial infectivity through catalyzing 3'3'-cGAMP degradation. Is specific for 3'3'-cGAMP since it cannot degrade ot [...] | Conserved hypothetical protein; Identified by Glimmer2; putative. | 0.522 |
| VC_A0681 | VC_A1083 | Conserved hypothetical protein; Phosphodiesterase (PDE) that catalyzes the hydrolysis of 3'3'-cyclic GMP-AMP (3'3'-cGAMP), leading to linear 5'-pApG. Also displays 5'-nucleotidase activity, further hydrolyzing 5'-pApG to 5'-ApG. Counteracts the function of the 3'3'-cGAMP synthase DncV, and is involved in the modulation of intracellular 3'3'-cGAMP levels. Enhances bacterial chemotaxis and inhibits intestinal colonization in vivo. Thus exerts a crucial role in regulating bacterial infectivity through catalyzing 3'3'-cGAMP degradation. Is specific for 3'3'-cGAMP since it cannot degrade ot [...] | Conserved hypothetical protein; Identified by Glimmer2; putative. | 0.683 |
| VC_A0714 | VC_A0802 | Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. | Conserved hypothetical protein; Identified by Glimmer2; putative. | 0.435 |
| VC_A0802 | VC_1538 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Hypothetical protein; Identified by Glimmer2; putative. | 0.426 |
| VC_A0802 | VC_A0536 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Conserved hypothetical protein; Identified by Glimmer2; putative. | 0.542 |
| VC_A0802 | VC_A0681 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Conserved hypothetical protein; Phosphodiesterase (PDE) that catalyzes the hydrolysis of 3'3'-cyclic GMP-AMP (3'3'-cGAMP), leading to linear 5'-pApG. Also displays 5'-nucleotidase activity, further hydrolyzing 5'-pApG to 5'-ApG. Counteracts the function of the 3'3'-cGAMP synthase DncV, and is involved in the modulation of intracellular 3'3'-cGAMP levels. Enhances bacterial chemotaxis and inhibits intestinal colonization in vivo. Thus exerts a crucial role in regulating bacterial infectivity through catalyzing 3'3'-cGAMP degradation. Is specific for 3'3'-cGAMP since it cannot degrade ot [...] | 0.522 |
| VC_A0802 | VC_A0714 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. | 0.435 |
| VC_A0802 | VC_A0803 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Serine protease, putative; Similar to PID:1336053; identified by sequence similarity; putative. | 0.573 |
| VC_A0802 | VC_A1083 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Conserved hypothetical protein; Identified by Glimmer2; putative. | 0.532 |
| VC_A0803 | VC_A0802 | Serine protease, putative; Similar to PID:1336053; identified by sequence similarity; putative. | Conserved hypothetical protein; Identified by Glimmer2; putative. | 0.573 |
| VC_A1083 | VC_A0536 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Conserved hypothetical protein; Identified by Glimmer2; putative. | 0.895 |
| VC_A1083 | VC_A0681 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Conserved hypothetical protein; Phosphodiesterase (PDE) that catalyzes the hydrolysis of 3'3'-cyclic GMP-AMP (3'3'-cGAMP), leading to linear 5'-pApG. Also displays 5'-nucleotidase activity, further hydrolyzing 5'-pApG to 5'-ApG. Counteracts the function of the 3'3'-cGAMP synthase DncV, and is involved in the modulation of intracellular 3'3'-cGAMP levels. Enhances bacterial chemotaxis and inhibits intestinal colonization in vivo. Thus exerts a crucial role in regulating bacterial infectivity through catalyzing 3'3'-cGAMP degradation. Is specific for 3'3'-cGAMP since it cannot degrade ot [...] | 0.683 |
| VC_A1083 | VC_A0802 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Conserved hypothetical protein; Identified by Glimmer2; putative. | 0.532 |