Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VC_A0813Aminopeptidase; Similar to PID:1694931; identified by sequence similarity; putative. (501 aa)    
Predicted Functional Partners:
VC_A0812
Leucine aminopeptidase-related protein; Similar to PID:1694931; identified by sequence similarity; putative.
 
  
0.842
gbpA
Chitinase, putative; Probably interacts with GlcNAc residues. May promote attachment to both epithelial cell surfaces and chitin. This function enhances bacterial colonization in the gastrointestinal tract and may also be important in the environment by augment colonization of chitinous structures, leading to improved survival. Promotes bacterial attachment to, and colonization of, zooplankton in the aquatic ecosystem; Belongs to the GbpA family.
 
  
 0.696
hutG
Formiminoglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.
 
 
 
 0.627
VC_1644
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.616
hap
Hemagglutinin/protease; May play a role in the pathogenesis of cholera. Hap nicks and activates the A subunit of cholera enterotoxin and related enterotoxins.
 
  
0.585
VC_A0218
Thermolabile hemolysin; Similar to GB:M36437 SP:Q99289 PID:155178; identified by sequence similarity; putative.
  
     0.563
VC_2622
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.558
VC_A0030
Hypothetical protein; Identified by Glimmer2; putative.
   
 
 0.548
VC_A0814
Agmatinase; Similar to GB:M32363 SP:P16936 PID:147859 PID:551839 PID:882466; identified by sequence similarity; putative; Belongs to the arginase family.
   
 
 0.548
prtV
Protease; Metalloprotease that exhibits a cytotoxic effect leading to cell death. In host tissues, it could play a role in pathogenesis by modulating the stability of the extracellular matrix components such as fibronectin and fibrinogen. Also able to cleave plasminogen.
  
   
 0.544
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.