Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_A0814Agmatinase; Similar to GB:M32363 SP:P16936 PID:147859 PID:551839 PID:882466; identified by sequence similarity; putative; Belongs to the arginase family. (309 aa)    
Predicted Functional Partners:
speA
Biosynthetic arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
 
 
 0.992
VC_1624
Conserved hypothetical protein; Involved in norspermidine biosynthesis. Catalyzes the synthesis of carboxynorspermidine from L-aspartate 4-semialdehyde and 1,3-diaminopropane. Is also active with putrescine as a substrate. Essential for biofilm formation; Belongs to the saccharopine dehydrogenase family. carboxynorspermidine synthase subfamily.
   
 0.944
VC_A1063
Ornithine decarboxylase, inducible; Similar to GB:M64495 SP:P24169 PID:147331 GB:U00096 PID:1651300; identified by sequence similarity; putative.
    
 0.909
speG
Spermidine n1-acetyltransferase; Involved in the protection against polyamine toxicity by regulating their concentration. Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to the primary amino groups of spermidine to yield N(1)- and N(8)-acetylspermidine. It can use polyamines such as spermine and N(1)-acetylspermine, but not putrescine or cadaverine; Belongs to the acetyltransferase family.
     
 0.905
leuS
leucyl-tRNA synthetase; Similar to SP:P07813 GB:X06331 PID:41916 GB:U00096 PID:1651269; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family.
    
   0.681
argD
Acetylornithine aminotransferase; Similar to GB:M32796 SP:P18335 PID:145337 PID:606293 GB:U00096; identified by sequence similarity; putative; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
  
 
 0.659
hutH
Histidine ammonia-lyase; Similar to GB:M35140 SP:P21310 PID:151274; identified by sequence similarity; putative; Belongs to the PAL/histidase family.
  
  
 0.578
VC_A0816
Hypothetical protein; Identified by Glimmer2; putative.
       0.576
hutI
Imidazolonepropionase; Similar to SP:P42084 PID:603768 GB:AL009126; identified by sequence similarity; putative; Belongs to the metallo-dependent hydrolases superfamily. HutI family.
  
  
 0.548
VC_A0813
Aminopeptidase; Similar to PID:1694931; identified by sequence similarity; putative.
   
 
 0.548
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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