Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
ectCEctoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (138 aa)    
Predicted Functional Partners:
ectA
L-2,4-diaminobutyric acid acetyltransferase; Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.
 
  
 0.997
ectB
Diaminobutyrate--pyruvate aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.972
VC_A0822
Aspartokinase, putative; Similar to GB:AE000782; identified by sequence similarity; putative.
 
   
 0.970
VC_0547
Aspartokinase, alpha and beta subunits; Similar to PID:928811 SP:P53553; identified by sequence similarity; putative; Belongs to the aspartokinase family.
     
 0.712
VC_0391
Aspartokinase III, lysine-sensitive; Similar to SP:P08660 GB:M11812 PID:146683 PID:396359 GB:U00096; identified by sequence similarity; putative; Belongs to the aspartokinase family.
     
 0.702
VC_1278
Transcriptional regulator, MarR family; Similar to GB:AL009126; identified by sequence similarity; putative.
 
  
 0.680
VC_0892
Chemotaxis protein PomA; Similar to PID:2130948; identified by sequence similarity; putative.
    
   0.655
VC_1206
Histidine utilization repressor; Similar to GB:M33922 SP:P22773 PID:151276; identified by sequence similarity; putative.
  
  
 0.626
VC_A0600
Repressor protein PhnR, putative; Similar to GP:1763080; identified by sequence similarity; putative.
  
  
 0.626
VC_1083
Hypothetical protein; Identified by Glimmer2; putative.
    
   0.611
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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