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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_A0827Pterin-4-alpha-carbinolamine dehydratase; Similar to GB:M88627 SP:P43335 PID:476742; identified by sequence similarity; putative. (109 aa)    
Predicted Functional Partners:
phhA
Phenylalanine-4-hydroxylase; Similar to GB:M88627 SP:P43334 PID:476741; identified by sequence similarity; putative.
 
 0.994
VC_1344
4-hydroxyphenylpyruvate dioxygenase; Similar to PID:2108220; identified by sequence similarity; putative.
  
  
 0.713
VC_1345
Oxidoreductase, putative; Similar to SP:Q00667 PID:984327; identified by sequence similarity; putative.
  
  
 0.681
VC_A0829
acetyl-CoA synthase; Similar to GB:AE000782; identified by sequence similarity; putative.
       0.576
VC_1293
Aspartate aminotransferase; Similar to SP:P00509 GB:X03629 GB:X05904 PID:41011 PID:41013; identified by sequence similarity; putative.
  
  
 0.521
VC_A0513
Amino acid biosynthesis aminotransferase; Similar to PID:1806263; identified by sequence similarity; putative.
  
  
 0.521
gph
Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
  
  
 0.515
VC_1059
Oxidoreductase, short-chain dehydrogenase/reductase family; Similar to SP:P31808 GB:U17433 PID:603171 GB:U00096 PID:1742066; identified by sequence similarity; putative.
  
 
 0.470
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
   
  
 0.419
rtxA
RTX toxin RtxA; [Multifunctional-autoprocessing repeats-in-toxin]: Precursor of a multifunctional toxin that causes destruction of the actin cytoskeleton by covalent cross-linking of actin and inactivation of Rho GTPases when translocated into the host cytoplasm. Upon translocation into the host cell, undergoes autoprocessing in cis mediated by the peptidase C80 domain (also named CPD domain): the protease activity is activated upon binding inositol hexakisphosphate (InsP6) present at the host cell membrane and delivers the Cysteine protease domain-containing toxin F3 chain to the host [...]
   
 
 0.419
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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