STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_A0827Pterin-4-alpha-carbinolamine dehydratase; Similar to GB:M88627 SP:P43335 PID:476742; identified by sequence similarity; putative. (109 aa)    
Predicted Functional Partners:
phhA
Phenylalanine-4-hydroxylase; Similar to GB:M88627 SP:P43334 PID:476741; identified by sequence similarity; putative.
 
 0.999
VC_1344
4-hydroxyphenylpyruvate dioxygenase; Similar to PID:2108220; identified by sequence similarity; putative.
  
  
 0.852
VC_A0829
acetyl-CoA synthase; Similar to GB:AE000782; identified by sequence similarity; putative.
     
 0.742
VC_1345
Oxidoreductase, putative; Similar to SP:Q00667 PID:984327; identified by sequence similarity; putative.
  
  
 0.632
VC_1293
Aspartate aminotransferase; Similar to SP:P00509 GB:X03629 GB:X05904 PID:41011 PID:41013; identified by sequence similarity; putative.
  
  
 0.600
VC_A0513
Amino acid biosynthesis aminotransferase; Similar to PID:1806263; identified by sequence similarity; putative.
  
  
 0.600
rtxA
RTX toxin RtxA; [Multifunctional-autoprocessing repeats-in-toxin]: Precursor of a multifunctional toxin that causes destruction of the actin cytoskeleton by covalent cross-linking of actin and inactivation of Rho GTPases when translocated into the host cytoplasm. Upon translocation into the host cell, undergoes autoprocessing in cis mediated by the peptidase C80 domain (also named CPD domain): the protease activity is activated upon binding inositol hexakisphosphate (InsP6) present at the host cell membrane and delivers the Cysteine protease domain-containing toxin F3 chain to the host [...]
  
   0.564
VC_A0490
Lipase, GDXG family; Similar to GB:AE000782; identified by sequence similarity; putative.
    
   0.544
VC_0705
Chorismate mutase/prephenate dehydratase; Similar to GB:L42023 SP:P43900 PID:1006481 PID:1221267 PID:1205390; identified by sequence similarity; putative.
      
 0.535
VC_1897
Hit family protein; Similar to GB:U00096 PID:1787346; identified by sequence similarity; putative.
   
   0.528
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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