STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_A0835Conserved hypothetical protein; Identified by Glimmer2; putative. (328 aa)    
Predicted Functional Partners:
VC_A0836
Hexapeptide-repeat containing-acetyltransferase; Similar to GB:D26185 SP:P37515 GB:L16865 PID:438465 PID:467369; identified by sequence similarity; putative.
       0.695
VC_A0059
Major outer membrane lipoprotein; Similar to GB:M13176 SP:P09461 GB:M28554 PID:150894 PID:150896; identified by sequence similarity; putative.
  
     0.559
VC_0153
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.553
VC_A0738
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.530
VC_1576
Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the UPF0267 family.
  
     0.527
rtxA
RTX toxin RtxA; [Multifunctional-autoprocessing repeats-in-toxin]: Precursor of a multifunctional toxin that causes destruction of the actin cytoskeleton by covalent cross-linking of actin and inactivation of Rho GTPases when translocated into the host cytoplasm. Upon translocation into the host cell, undergoes autoprocessing in cis mediated by the peptidase C80 domain (also named CPD domain): the protease activity is activated upon binding inositol hexakisphosphate (InsP6) present at the host cell membrane and delivers the Cysteine protease domain-containing toxin F3 chain to the host [...]
 
   
 0.501
alaE
Conserved hypothetical protein; Exports L-alanine; Belongs to the AlaE exporter family.
  
   
 0.490
VC_1636
Helicase-related protein; Similar to SP:P36927 GB:U00096; identified by sequence similarity; putative.
  
 0.464
VC_A0568
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.461
VC_A0838
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
     0.447
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.