STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_A0849Hypothetical protein; Identified by Glimmer2; putative. (3263 aa)    
Predicted Functional Partners:
VC_1280
Hypothetical protein; Identified by Glimmer2; putative.
 
  
 0.950
VC_0414
Hypothetical protein; Identified by Glimmer2; putative.
  
 0.935
VC_1250
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
 
 0.883
rtxA
RTX toxin RtxA; [Multifunctional-autoprocessing repeats-in-toxin]: Precursor of a multifunctional toxin that causes destruction of the actin cytoskeleton by covalent cross-linking of actin and inactivation of Rho GTPases when translocated into the host cytoplasm. Upon translocation into the host cell, undergoes autoprocessing in cis mediated by the peptidase C80 domain (also named CPD domain): the protease activity is activated upon binding inositol hexakisphosphate (InsP6) present at the host cell membrane and delivers the Cysteine protease domain-containing toxin F3 chain to the host [...]
  
 
 0.879
VC_A0576
Heme transport protein HutA; Similar to GB:L27149 PID:529727; identified by sequence similarity; putative.
  
 
 
 0.862
VC_A0064
TonB system receptor, putative; Similar to GB:L27149 PID:529727; identified by sequence similarity; putative.
  
 
 
 0.847
viuA
Ferric vibriobactin receptor; Receptor for ferric vibriobactin; Belongs to the TonB-dependent receptor family.
    
 
 0.811
VC_A0625
TonB receptor-related protein; Similar to PID:1638846; identified by sequence similarity; putative.
    
 
 0.811
VC_2125
Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
   
 
 0.798
vcc
Collagenase; Possesses gelatinolytic activity; Belongs to the peptidase M9A family.
 
  
  0.797
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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