Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VC_A0850Response regulator; Similar to GB:M23230 SP:P26275 PID:151004 PID:1196739; identified by sequence similarity; putative. (261 aa)    
Predicted Functional Partners:
VC_A0851
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
  
 0.941
VC_0694
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
 
 0.909
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
    
   0.621
VC_A0853
Hypothetical protein; Identified by Glimmer2; putative.
 
     0.618
VC_A0855
ABC transporter, ATP-binding protein; Similar to GB:AE000782; identified by sequence similarity; putative.
 
     0.550
VC_A0852
Hypothetical protein; Identified by Glimmer2; putative.
       0.541
VC_A0854
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.541
rfbB
Phosphomannomutase; Involved in GDP-mannose biosynthesis which serves as the activated sugar nucleotide precursor for mannose residues in cell surface polysaccharides; Belongs to the phosphohexose mutase family.
   
  
 0.540
VC_1320
DNA-binding response regulator; Similar to PID:1079807 SP:P52108 GB:U00096 PID:1742647 PID:1742658; identified by sequence similarity; putative.
  
   
 0.514
VC_A0849
Hypothetical protein; Identified by Glimmer2; putative.
 
  
 0.501
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: high (92%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.