STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dsdAD-serine dehydratase; Similar to GB:J01603 SP:P00926 GB:X86379 PID:145806 GB:U00096; identified by sequence similarity; putative; Belongs to the serine/threonine dehydratase family. DsdA subfamily. (441 aa)    
Predicted Functional Partners:
ilvA
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
     
0.666
VC_A0666
L-serine dehydratase 1; Similar to GB:M28695 SP:P16095 PID:290464 GB:U00096 PID:1736451; identified by sequence similarity; putative; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.654
VC_A0876
D-serine deaminase activator; Similar to SP:P46068 PID:1050466 GB:U00096 PID:1788706 PID:1799763; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
 
     0.608
VC_A0192
D-lactate dehydrogenase; Similar to PID:1049265 SP:P52643 GB:U00096 PID:1742253 PID:1742259; identified by sequence similarity; putative; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
     
 0.606
VC_1300
L-serine dehydratase 1; Similar to GB:M28695 SP:P16095 PID:290464 GB:U00096 PID:1736451; identified by sequence similarity; putative; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.560
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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