Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_A0890Glyoxylase I family protein; Similar to GB:U00096 PID:1552764 PID:1786385 PID:971393; identified by sequence similarity; putative. (127 aa)    
Predicted Functional Partners:
VC_A0889
Transcriptional regulator, LysR family; Similar to PID:924993 SP:P52689; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
       0.849
VC_0058
Carbonic anhydrase, family 3; Similar to GB:AE000657; identified by sequence similarity; putative.
 
    0.686
gloB
Hydroxyacylglutathione hydrolase GloB, putative; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
   
 0.548
VC_A0888
Transcriptional regulator, LuxR family; Similar to GB:M98835 SP:Q03316 PID:152430; identified by sequence similarity; putative.
       0.526
VC_0716
Ferredoxin; Similar to GB:L42023 PID:1003938 PID:1222462 PID:1204778 SP:P44746; identified by sequence similarity; putative.
  
    0.491
birA
birA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
    0.483
VC_2126
Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
    
   0.482
tadA
yfhC protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
   
  
 0.461
VC_1083
Hypothetical protein; Identified by Glimmer2; putative.
    
   0.460
VC_A0189
Response regulator; Similar to PID:1736859 PID:1736868; identified by sequence similarity; putative.
    
   0.460
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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