STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_A0891Conserved hypothetical protein; Identified by Glimmer2; putative. (470 aa)    
Predicted Functional Partners:
VC_A0924
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
  
 0.801
cysI
Sulfite reductase (NADPH) hemoprotein beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
    
 0.661
VC_A0620
Thiosulfate sulfurtransferase SseA, putative; Similar to SP:P31142 GB:U00096 PID:1788869 PID:1799924; identified by sequence similarity; putative.
     
 0.614
VC_1512
Formate dehydrogenase, iron-sulfur subunit; Similar to SP:P27273 PID:48508; identified by sequence similarity; putative.
     
 0.613
VC_A0892
Hypothetical protein; Identified by Glimmer2; putative.
       0.571
hmp
Ferrisiderophore reductase; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity). Belongs to the globin family. Two-domain flavohemoproteins subfamily.
 
  
 0.551
tagA
ToxR-activated gene A protein; Similar to GP:3004926; identified by sequence similarity; putative.
    
  0.523
VC_A0148
TagA-related protein; Similar to GB:U12265 SP:P24019 PID:516033; identified by sequence similarity; putative.
    
  0.523
cysH
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
     
 0.516
cysD
Sulfate adenylate transferase, subunit 2; Similar to GB:M74586 SP:P21156 PID:145669 PID:145672 PID:882645; identified by sequence similarity; putative.
     
 0.516
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.