STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
VC_A08986-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (482 aa)    
Predicted Functional Partners:
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
 0.998
VC_0287
Thermoresistant gluconokinase; Similar to SP:P46859 PID:606372 GB:U00096 PID:1304070 PID:1789845; identified by sequence similarity; putative.
  
 0.994
pgl
devB protein; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
 
 
 0.994
VC_2625
Ribulose-phosphate 3-epimerase; Similar to SP:P32661 GB:Z19601 PID:41222 GB:U00096 PID:1789788; identified by sequence similarity; putative; Belongs to the ribulose-phosphate 3-epimerase family.
   
 0.971
tal
Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 
 0.950
rpiA
Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
   
 
 0.934
edd
Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.
   
 0.930
tkt1
Transketolase 1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.918
tkt2
Transketolase 1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.918
pgk
Phosphoglycerate kinase; Similar to SP:P11665 PID:41422 PID:882455 GB:U00096 PID:1789294; identified by sequence similarity; putative; Belongs to the phosphoglycerate kinase family.
   
 
 0.816
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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