STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hutZConserved hypothetical protein; Involved in heme degradation. Catalyzes the degradation of heme to biliverdin, with the release of iron. Forms biliverdin beta and delta. Binds heme with high efficiency. (176 aa)    
Predicted Functional Partners:
hutX
Conserved hypothetical protein; Binds heme. Heme is transferred to the heme-degrading enzyme HutZ via a specific protein- protein interaction.
 
  
 0.972
VC_A0909
Oxygen-independent coproporphyrinogen III oxidase, putative; Similar to SP:P54304 PID:1303805 GB:AL009126; identified by sequence similarity; putative.
 
   
 0.881
VC_A0530
Pyruvate-flavoredoxin oxidoreductase; Similar to GB:U00096 PID:1742250 PID:1742256 PID:1787642; identified by sequence similarity; putative.
    
   0.833
exbD1
TonB system transport protein ExbD1; Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
 
  
 0.741
VC_A0914
Hemin ABC transporter, permease protein, putative; Similar to GP:2738774; identified by sequence similarity; putative; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
  
 0.686
VC_0202
iron(III) ABC transporter, periplasmic iron-compound-binding protein; Similar to GB:D26562 SP:P07822 GB:M12486 PID:145951 PID:41441; identified by sequence similarity; putative.
 
    0.674
VC_A0576
Heme transport protein HutA; Similar to GB:L27149 PID:529727; identified by sequence similarity; putative.
 
  
 0.669
btuF
Conserved hypothetical protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
  
    0.656
VC_A0913
Hemin ABC transporter, periplasmic hemin-binding protein HutB; Similar to GP:2738773; identified by sequence similarity; putative.
 
  
 0.652
VC_0608
iron(III) ABC transporter, periplasmic iron-compound-binding protein; Similar to PID:1651916; identified by sequence similarity; putative.
   
    0.634
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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