Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_A0914Hemin ABC transporter, permease protein, putative; Similar to GP:2738774; identified by sequence similarity; putative; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (343 aa)    
Predicted Functional Partners:
hmuV
Hemin ABC transporter, ATP-binding protein HutD; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.
 
 
 0.992
VC_A0913
Hemin ABC transporter, periplasmic hemin-binding protein HutB; Similar to GP:2738773; identified by sequence similarity; putative.
 
 
 0.990
VC_0201
iron(III) ABC transporter, ATP-binding protein; Similar to PID:41440 GB:U00096 PID:1552729 PID:1786345; identified by sequence similarity; putative.
 
 
 0.972
VC_0779
Ferric vibriobactin ABC transporter, ATP-binding protein; Similar to SP:P23878 GB:X57471 PID:41432 GB:U00096 PID:1778504; identified by sequence similarity; putative.
 
 
 0.970
btuF
Conserved hypothetical protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
 
 
 0.903
exbB1
TonB system transport protein ExbB1; Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity).
  
  
 0.857
exbD1
TonB system transport protein ExbD1; Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
  
  
 0.856
tonB
tonB1 protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins (By similarity).
     
 0.854
VC_A0229
iron(III) ABC transporter, permease protein; Similar to GB:AL009126; identified by sequence similarity; putative; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
  
  
 0.826
hutX
Conserved hypothetical protein; Binds heme. Heme is transferred to the heme-degrading enzyme HutZ via a specific protein- protein interaction.
     
 0.816
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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