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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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hmuVHemin ABC transporter, ATP-binding protein HutD; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system. (236 aa)    
Predicted Functional Partners:
VC_A0913
Hemin ABC transporter, periplasmic hemin-binding protein HutB; Similar to GP:2738773; identified by sequence similarity; putative.
 
 
 0.993
VC_A0914
Hemin ABC transporter, permease protein, putative; Similar to GP:2738774; identified by sequence similarity; putative; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.992
VC_0777
Ferric vibriobactin ABC transporter, permease protein; Similar to SP:P23876 GB:U15411 GB:X57471 GB:X59402 PID:41430; identified by sequence similarity; putative; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.970
VC_0203
iron(III) ABC transporter, permease protein; Similar to GB:D26562 SP:P06972 PID:41447 PID:473812 PID:581081; identified by sequence similarity; putative; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.965
btuC
Vitamin B12 ABC transporter, permease protein BtuC, putative; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.
  
   
 0.846
tonB
tonB1 protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins (By similarity).
     
 0.840
exbB1
TonB system transport protein ExbB1; Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity).
     
 0.829
exbD1
TonB system transport protein ExbD1; Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
     
 0.829
hutX
Conserved hypothetical protein; Binds heme. Heme is transferred to the heme-degrading enzyme HutZ via a specific protein- protein interaction.
 
   
 0.814
hutZ
Conserved hypothetical protein; Involved in heme degradation. Catalyzes the degradation of heme to biliverdin, with the release of iron. Forms biliverdin beta and delta. Binds heme with high efficiency.
 
   
 0.781
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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