STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
speGSpermidine n1-acetyltransferase; Involved in the protection against polyamine toxicity by regulating their concentration. Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to the primary amino groups of spermidine to yield N(1)- and N(8)-acetylspermidine. It can use polyamines such as spermine and N(1)-acetylspermine, but not putrescine or cadaverine; Belongs to the acetyltransferase family. (173 aa)    
Predicted Functional Partners:
VC_A0814
Agmatinase; Similar to GB:M32363 SP:P16936 PID:147859 PID:551839 PID:882466; identified by sequence similarity; putative; Belongs to the arginase family.
     
 0.905
VC_1624
Conserved hypothetical protein; Involved in norspermidine biosynthesis. Catalyzes the synthesis of carboxynorspermidine from L-aspartate 4-semialdehyde and 1,3-diaminopropane. Is also active with putrescine as a substrate. Essential for biofilm formation; Belongs to the saccharopine dehydrogenase family. carboxynorspermidine synthase subfamily.
   
 
  0.902
VC_A1063
Ornithine decarboxylase, inducible; Similar to GB:M64495 SP:P24169 PID:147331 GB:U00096 PID:1651300; identified by sequence similarity; putative.
     
 0.902
VC_A0948
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.849
VC_0917
UDP-N-acetylglucosamine 2-epimerase; Similar to GB:M87049 SP:P27828 GB:L18799 PID:148189 PID:304919; identified by sequence similarity; putative; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
     
 0.594
VC_A0436
Acetyltransferase, putative; Similar to GB:AL009126; identified by sequence similarity; putative.
 
   
 0.535
VC_A0505
Acetyltransferase, putative; Similar to SP:P05332 GB:X07542 PID:39573; identified by sequence similarity; putative.
 
   
 0.518
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
   
    0.457
malK
Maltose/maltodextrin ABC transporter, ATP-binding protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family.
       0.433
VC_1309
Ribosomal-protein-alanine acetyltransferase; Similar to GB:M99278 SP:P09454 GB:X06118 PID:147655 PID:42744; identified by sequence similarity; putative.
  
   
 0.407
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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