STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_A0957Malate synthase-related protein; Similar to SP:P37330 GB:X74547 PID:517247 PID:882505 GB:U00096; identified by sequence similarity; putative. (202 aa)    
Predicted Functional Partners:
VC_0736
Isocitrate lyase; Similar to SP:P05313 GB:M20714 GB:M22621 GB:X07543 GB:X12431; identified by sequence similarity; putative.
  
 
 0.951
VC_1337
Methylcitrate synthase; Similar to GB:U00096 PID:1657529 PID:1786527; identified by sequence similarity; putative; Belongs to the citrate synthase family.
  
 
 0.832
VC_A0958
Hypothetical protein; Identified by Glimmer2; putative.
 
   
 0.831
VC_2092
Citrate synthase; Similar to GB:J01619 SP:P00891 GB:M28987 GB:M28988 GB:V01501; identified by sequence similarity; putative; Belongs to the citrate synthase family.
   
 
 0.804
pta
Phosphate acetyltransferase; Involved in acetate metabolism; In the N-terminal section; belongs to the CobB/CobQ family.
  
  
 0.799
prpB
Carboxyphosphonoenolpyruvate phosphonomutase; Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage reaction of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.
  
 
 0.759
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
   
 0.689
VC_A0808
NodN-related protein; Similar to GB:AL123456; identified by sequence similarity; putative.
  
  
 0.654
ackA1
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
  
 0.590
ackA2
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
  
 0.590
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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