Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_A0983L-lactate permease, putative; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (582 aa)    
Predicted Functional Partners:
lldD
L-lactate dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
  
  
 0.971
VC_A0985
Oxidoreductase/iron-sulfur cluster-binding protein; Similar to GB:AE000511 PID:2314381; identified by sequence similarity; putative.
 
  
 0.920
VC_1198
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
  
 0.752
VC_A0982
Transcriptional regulator, LysR family; Similar to PID:1652750; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
     
 0.742
VC_2415
Pyruvate dehydrogenase complex repressor; Similar to PID:455922 GB:U00096 SP:P06957 PID:1786303 PID:434009; identified by sequence similarity; putative.
 
  
 0.725
VC_A0530
Pyruvate-flavoredoxin oxidoreductase; Similar to GB:U00096 PID:1742250 PID:1742256 PID:1787642; identified by sequence similarity; putative.
     
 0.622
VC_A0749
Anaerobic glycerol-3-phosphate dehydrogenase, subunit C; Similar to GB:M20938 SP:P13034 PID:146179 GB:U00096 PID:1788576; identified by sequence similarity; putative.
 
  
 0.607
pta
Phosphate acetyltransferase; Involved in acetate metabolism; In the N-terminal section; belongs to the CobB/CobQ family.
     
 0.582
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
  
  
 0.561
VC_0136
Conserved hypothetical protein; Involved in positive regulation of motility and negative regulation of biofilm formation.
      
 0.559
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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