Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VC_A1008Outer membrane protein, putative; Similar to PID:1658032; identified by sequence similarity; putative. (331 aa)    
Predicted Functional Partners:
ompU
Outer membrane protein OmpU; Forms pores that allow passive diffusion of small molecules across the outer membrane.
  
  
 
0.922
VC_0972
Porin, putative; Similar to SP:P24305; identified by sequence similarity; putative.
     
  0.900
VC_1854
Porin, putative; Similar to GP:3377759; identified by sequence similarity; putative.
     
  0.900
VC_2213
Outer membrane protein OmpA; Similar to GP:2641145; identified by sequence similarity; putative; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
   
 0.806
btuB
Vitamin B12 receptor; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
  
 
 0.803
VC_2048
vacJ lipoprotein; Similar to GB:U00096 SP:P76506 PID:1788688 PID:1799744; identified by sequence similarity; putative.
   
 
 0.767
lapA
Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.
  
     0.739
zapB
Conserved hypothetical protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.
  
     0.724
VC_2276
Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the UPF0255 family.
  
  
 0.719
VC_0132
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.716
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.