Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VC_A1043tagE protein; Similar to GB:AE000511 PID:2314724; identified by sequence similarity; putative. (314 aa)    
Predicted Functional Partners:
VC_A1042
Ccm2-related protein; Similar to GB:AE000511 PID:2314731; identified by sequence similarity; putative.
 
   
 0.887
VC_0533
Lipoprotein NlpD; Similar to GP:2897901; identified by sequence similarity; putative.
 
   
 0.750
VC_0335
NlpD-related protein; Similar to SP:P37690 PID:466751 GB:U00096 PID:1790042; identified by sequence similarity; putative.
 
   
 0.707
VC_1537
Lipoprotein NlpC; Similar to GB:M14031 SP:P23898 PID:145446 GB:U00096 PID:1742788; identified by sequence similarity; putative.
  
  
 0.592
VC_2081
Zinc ABC transporter, periplasmic zinc-binding protein; Similar to GB:U00096 SP:P39172 PID:1736500 PID:1788164; identified by sequence similarity; putative; Belongs to the bacterial solute-binding protein 9 family.
 
  
 0.521
VC_1268
Conserved hypothetical protein; Identified by Glimmer2; putative.
      
 0.514
mrcA
Penicillin-binding protein 1A; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
  
   
 0.497
trpR
Trp operon repressor, putative; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription (By similarity).
  
    0.484
VC_2462
Signal peptidase I; Similar to SP:P23697 GB:X52093 GB:X54933 PID:47757; identified by sequence similarity; putative; Belongs to the peptidase S26 family.
  
  
 0.484
VC_2126
Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
    
   0.482
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.