STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
mtlAPTS system, mannitol-specific IIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in D-mannitol transport. (649 aa)    
Predicted Functional Partners:
VC_1822
PTS system, fructose-specific IIABC component; Similar to GB:AL009126; identified by sequence similarity; putative.
 
 
 0.999
VC_1826
PTS system, fructose-specific IIABC component; Similar to GB:AL009126; identified by sequence similarity; putative.
 
 
 0.999
mtlD
Mannitol-1-phosphate 5-dehydrogenase; Similar to SP:P09424 GB:X51359 PID:42039 PID:466738 GB:U00096; identified by sequence similarity; putative.
 
 0.999
VC_A0516
PTS system, fructose-specific IIBC component; Similar to SP:P20966 GB:M23196 PID:405893 PID:450372 GB:U00096; identified by sequence similarity; putative.
 
 
 0.994
VC_A0518
PTS system, fructose-specific IIA/FPR component; Similar to PID:619247 SP:P24217 GB:U00096 PID:1736835 PID:1788494; identified by sequence similarity; putative.
 
0.994
VC_1821
PTS system, fructose-specific IIBC component; Similar to SP:P32672 GB:U00006 PID:396296 GB:U00096 PID:1790386; identified by sequence similarity; putative.
 
 
 0.993
VC_1824
PTS system, nitrogen regulatory IIA component, putative; Similar to GB:U00096 PID:1788726 PID:1799794; identified by sequence similarity; putative.
  
 0.991
ptsH
Phosphocarrier protein HPr; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
 
 
 0.974
npr
Phosphocarrier protein NPr; Component of the phosphoenolpyruvate-dependent nitrogen- metabolic phosphotransferase system (nitrogen-metabolic PTS), that seems to be involved in regulating nitrogen metabolism. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein NPr by enzyme I-Ntr. Phospho-NPr then transfers it to EIIA-Ntr. Could function in the transcriptional regulation of sigma-54 dependent operons in conjunction with the NPr (PtsO) and EIIA-Ntr (PtsN) proteins; Belongs to the HPr family.
   
 0.971
VC_1820
PTS system, fructose-specific IIA component; Similar to SP:P32155 GB:X60472 PID:396682 PID:305004 GB:U00096; identified by sequence similarity; putative.
 
 
 0.965
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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