Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VC_A1058Transcriptional regulator, LysR family; Similar to PID:1493807; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family. (301 aa)    
Predicted Functional Partners:
VC_A1057
Oxidoreductase, short-chain dehydrogenase/reductase family; Similar to PID:1001780 PID:1001805; identified by sequence similarity; putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
   
 0.911
VC_2324
Transcriptional regulator, LysR family; Similar to SP:P32484 PID:405876 PID:466777 GB:U00096 PID:1788481; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
     0.700
VC_1561
Transcriptional regulator, LysR family; Similar to SP:P10183 PID:150233; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
     0.662
VC_0732
Transcriptional regulator, LysR family; Similar to PID:887385 SP:P52667 PID:1359475; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
     0.632
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).
  
 
 
 0.594
VC_2485
Transcriptional regulator, LysR family; Similar to GB:D10483 SP:P10151 GB:M21150 PID:1128961 PID:146605; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
     0.565
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.542
VC_A1059
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.533
VC_A1020
Transcriptional regulator, LysR family; Similar to PID:1684731; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
     0.522
VC_1706
Transcriptional activator MetR; Similar to GB:M17356 SP:P05984 PID:154177; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
     0.521
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (16%) [HD]