close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_A1109Hypothetical protein; Identified by Glimmer2; putative. (236 aa)    
Predicted Functional Partners:
VC_A1110
long-chain-fatty-acid--CoA ligase, putative; Similar to GP:3293047; identified by sequence similarity; putative.
  
 0.994
VC_A1108
Oxidoreductase, short-chain dehydrogenase/reductase family; Similar to GB:M84991 SP:P25716 PID:145881 PID:145888 GB:U00096; identified by sequence similarity; putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
   
 0.956
VC_A1111
Thermostable hemolysin; Similar to GP:3293046; identified by sequence similarity; putative.
 
   
 0.951
VC_1296
Phosphomethylpyrimidine kinase; Similar to GB:U00096 SP:P76422 PID:1788420; identified by sequence similarity; putative.
  
 
 0.949
VC_A1106
Hypothetical protein; Identified by Glimmer2; putative.
 
     0.949
VC_A1107
Hypothetical protein; Identified by Glimmer2; putative.
 
     0.949
VC_A1105
DNA-binding response regulator; Similar to PID:882555 SP:P52076 GB:U00096 PID:1789402; identified by sequence similarity; putative.
 
     0.840
thiE
Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
 
 0.835
thiC
Thiamin biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
 
 0.833
VC_0064
thiS protein; Similar to PID:1469147; identified by sequence similarity; putative.
 
    0.709
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.