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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_A1110long-chain-fatty-acid--CoA ligase, putative; Similar to GP:3293047; identified by sequence similarity; putative. (507 aa)    
Predicted Functional Partners:
VC_A1109
Hypothetical protein; Identified by Glimmer2; putative.
  
 0.994
VC_A1111
Thermostable hemolysin; Similar to GP:3293046; identified by sequence similarity; putative.
 
   
 0.952
VC_A1108
Oxidoreductase, short-chain dehydrogenase/reductase family; Similar to GB:M84991 SP:P25716 PID:145881 PID:145888 GB:U00096; identified by sequence similarity; putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
   
 0.945
VC_A1106
Hypothetical protein; Identified by Glimmer2; putative.
 
     0.940
VC_A1107
Hypothetical protein; Identified by Glimmer2; putative.
 
     0.940
VC_A1105
DNA-binding response regulator; Similar to PID:882555 SP:P52076 GB:U00096 PID:1789402; identified by sequence similarity; putative.
 
  
  0.856
VC_0249
rfbL protein; Similar to GB:X59554 PID:48391; identified by sequence similarity; putative.
 
  
 0.803
rplE
Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
    
 
 0.794
VC_1349
Sensory box sensor histidine kinase/response regulator; Similar to PID:1653075; identified by sequence similarity; putative.
    
 0.762
VC_1653
Sensory box sensor histidine kinase/response regulator VieS; Similar to GP:3123890; identified by sequence similarity; putative.
    
 0.762
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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