Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VC_A1111Thermostable hemolysin; Similar to GP:3293046; identified by sequence similarity; putative. (200 aa)    
Predicted Functional Partners:
VC_A1109
Hypothetical protein; Identified by Glimmer2; putative.
 
   
 0.968
VC_A1110
long-chain-fatty-acid--CoA ligase, putative; Similar to GP:3293047; identified by sequence similarity; putative.
 
   
 0.966
VC_A1108
Oxidoreductase, short-chain dehydrogenase/reductase family; Similar to GB:M84991 SP:P25716 PID:145881 PID:145888 GB:U00096; identified by sequence similarity; putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
   
 0.965
VC_A1107
Hypothetical protein; Identified by Glimmer2; putative.
 
   
 0.947
VC_A1106
Hypothetical protein; Identified by Glimmer2; putative.
 
   
 0.946
VC_A1105
DNA-binding response regulator; Similar to PID:882555 SP:P52076 GB:U00096 PID:1789402; identified by sequence similarity; putative.
 
     0.872
VC_0040
Hemolysin, putative; Similar to PID:887849 GB:U00096 PID:1789266; identified by sequence similarity; putative.
      
 0.543
tmcA
Conserved hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
       0.460
ompU
Outer membrane protein OmpU; Forms pores that allow passive diffusion of small molecules across the outer membrane.
  
   
 0.452
VC_A0218
Thermolabile hemolysin; Similar to GB:M36437 SP:Q99289 PID:155178; identified by sequence similarity; putative.
      
 0.428
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (12%) [HD]