Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (898 aa)    
Predicted Functional Partners:
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
  
  
 0.954
pykF
Pyruvate kinase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0469; Belongs to the pyruvate kinase family.
     
 0.948
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
     
 0.928
gltB
Glutamate synthase, large subunit; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0069.
  
  
 0.895
pgk
Phosphoglycerate kinase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0126; Belongs to the phosphoglycerate kinase family.
  
 
 0.891
aceB
Malate synthase A; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG2225; Belongs to the malate synthase family.
     
 0.856
pgm
Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
     
 0.847
fdoH
Formate dehydrogenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0437/TC:5.A.3.2.1.
     
 0.843
gtlA
Citrate (si)-synthase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0372; Belongs to the citrate synthase family.
     
 0.842
prpC
Citrate synthase 2; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0372; Belongs to the citrate synthase family.
     
 0.842
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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