STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdxHPyridoxamine-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (213 aa)    
Predicted Functional Partners:
pdxJ
Pyridoxal phosphate biosynthetic protein pdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
  
  
 0.939
pyrB
Aspartate carbamoyltransferase catalytic chain; Identified by sequence similarity; putative; ORF located using Blastx/COG0540; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
      0.866
CV_0565
Hypothetical protein.
      0.843
carB
Carbamoyl-phosphate synthase large chain; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0458; Belongs to the CarB family.
 
 
  
 0.629
CV_4157
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG3217.
 
      0.586
CV_0060
Probable endonuclease; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx.
       0.527
gcvP
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
 
   
 0.525
lasB
Class 4 metalloprotease; Extracellular zinc metalloprotease.
  
    0.518
hemF
Coproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
  
    0.481
entB
Isochorismatase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1535.
  
  
 0.460
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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