STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLGlutamate-1-semialdehyde 2,1-aminomutase; Identified by sequence similarity; putative; ORF located using Blastx/COG0001. (425 aa)    
Predicted Functional Partners:
hemB
Porphobilinogen synthase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0113; Belongs to the ALAD family.
 
 
 0.994
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.991
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.949
entF
Enterobactin synthetase component F; Identified by sequence similarity; putative; ORF located using Blastx/COG1020.
  
 
 0.946
CV_2819
Probable glutamate-1-semialdehyde aminotransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0001; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 
0.921
CV_0803
Probable 5-aminolevulinate synthase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0156.
     
 0.905
CV_2803
Probable peptide synthetase protein; Identified by sequence similarity; putative; ORF located using Blastx/COG1020/TC:9.B.17.1.6.
  
 
 0.878
cbsF
Synthetase CbsF; Identified by sequence similarity; putative; ORF located using Blastx/COG0365/TC:9.B.17.1.4.
  
 
 0.800
CV_3949
Probable 3-oxoacyl-[acyl-carrier-protein] synthase II; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0304; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 
  
 0.737
cobA1
uroporphyrin-III C-methyltransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0007; Belongs to the precorrin methyltransferase family.
 
   
 0.727
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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