STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pilRTwo-component system, regulatory protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2204. (437 aa)    
Predicted Functional Partners:
pilS
Two-component system sensor protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0642.
 0.997
rpoN
RNA polymerase N (sigma54) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.963
parC
DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
     
 0.790
pilZ
Type 4 fimbrial biogenesis protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG3215.
  
   
 0.782
pilM
Type 4 fimbrial biogenesis protein PilM; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0849.
 
   
 0.746
CV_0841
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/COG2199.
  
 
 0.722
fleN
Flagellar synthesis regulator FleN; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0455.
  
 
 0.681
ntrB
Two-component sensor NtrB; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0642.
 
 0.679
CV_3089
Probable two-component system; Identified by sequence similarity; putative; ORF located using Blastx/COG0642.
 
 
 
 0.647
pilW
Type 4 fimbrial biogenesis transmembrane protein; Identified by sequence similarity; putative; ORF located using Blastx.
      
 0.642
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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