Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pilSTwo-component system sensor protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0642. (518 aa)    
Predicted Functional Partners:
pilR
Two-component system, regulatory protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2204.
 0.997
rpoN
RNA polymerase N (sigma54) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
     
 0.909
CV_3503
Probable sensor/response regulator hybrid; Identified by sequence similarity; putative; ORF located using Blastx/COG0784.
 
 
 0.849
parC
DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
     
 0.797
CV_1621
Probable sensor/response regulatory hybrid protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0784.
  
 
 0.792
CV_2766
Probable transmembrane protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG3170/TC:3.D.3.1.1.
  
 
   0.779
CV_1951
Probable two-component sensor; Identified by sequence similarity; putative; ORF located using Blastx/COG0784.
  
 
 0.772
CV_2643
Probable sensor/response regulator hybrid; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0784.
  
 
 0.772
CV_3248
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/COG0784.
  
 
 0.772
CV_1579
Probable two-component hybrid sensor and regulator; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0784.
 
 
 0.768
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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