Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CV_0097Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx. (273 aa)    
Predicted Functional Partners:
cbiJ
precorrin-3B C17-methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/COG1010.
  
  
 0.929
cbiF
Precorrin-4 C11-methyltransferase protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG2875; Belongs to the precorrin methyltransferase family.
  
  
 0.838
cbiL
Precorrin-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A.
  
  
 0.791
cbiC
precorrin-8X methylmutase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2082.
  
  
 0.701
cbiD
Cobalamin biosynthesis cbiD transmembrane protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
  
  
 0.627
cobQ
Cobyric acid synthase protein; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
  
 0.618
cbiG
Precorrin methylase protein; Identified by sequence similarity; putative; ORF located using Blastx/COG2073.
  
  
 0.574
CV_2927
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx.
  
    0.552
CV_1379
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx.
  
     0.550
CV_0626
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/COG3308.
  
     0.492
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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