Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mdmCO-methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx. (221 aa)    
Predicted Functional Partners:
CV_0194
Probable glutathione transferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0625.
   
   0.718
talA
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
  
  
 0.611
cafA
Ribonuclease G; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1530.
      
 0.576
CV_0266
Probable collagenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0826.
  
  
 0.539
CV_1955
Probable protease; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0826.
  
  
 0.539
CV_4084
Probable protease; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0826.
  
  
 0.539
CV_4085
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0826.
  
  
 0.539
tktA
Transketolase 1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
     
 0.523
CV_0195
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1846.
       0.515
CV_3513
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG3220; Belongs to the UPF0276 family.
   
    0.503
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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