Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CV_0225Probable 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (424 aa)    
Predicted Functional Partners:
lpxK
Tetraacyldisaccharide 4`-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
 0.998
rfaC
Lipopolysaccharide heptosyltransferase I; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0859.
  
 0.997
htrB
Lipid A biosynthesis lauroyl acyltransferase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1560.
 
  
 0.979
CV_0962
Probable acyltransferase transmembrane protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1560.
 
  
 0.974
kdsB
3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
 
  
 0.970
rfaQ
Lipopolysaccharide glucosyltransferase I; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0859.
  
 0.963
rfaF
ADP-heptose--LPS heptosyltransferase II; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0859.
 
  
 0.955
CV_0820
Probable O-antigen ligase; Identified by sequence similarity; putative; ORF located using Blastx/COG3307.
    
 0.920
CV_0817
Probable glycosyltransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0438.
    
 0.907
CV_3327
Probable KpsF/GutQ family protein; Identified by sequence similarity; putative; ORF located using Blastx/COG0517; Belongs to the SIS family. GutQ/KpsF subfamily.
 
   
 0.861
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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