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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tyrB2Aromatic-amino-acid transaminase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1448. (397 aa)    
Predicted Functional Partners:
hpd
4-hydroxyphenylpyruvate dioxygenase; Identified by sequence similarity; putative; ORF located using Blastx/COG3185.
  
 
 0.956
phhA
Phenylalanine 4-monooxygenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG3186; Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
  
 
 0.952
pheA
Chorismate mutase/prephenate dehydratase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1605.
    
 0.944
CV_3407
Probable prephenate dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/COG0287.
    
 0.925
CV_0203
Probable 5-methyltetrahydrofolate-homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.921
CV_0038
Probable histidinol-phosphate aminotransferase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0079.
   
 
 0.914
hisC
Histidinol-phosphate aminotransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0079; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
   
 
 0.914
CV_2004
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1956.
    
  0.910
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
     
 0.909
CV_2363
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/Blastx/COG1956.
    
  0.906
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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