STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tyrB2Aromatic-amino-acid transaminase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1448. (397 aa)    
Predicted Functional Partners:
hpd
4-hydroxyphenylpyruvate dioxygenase; Identified by sequence similarity; putative; ORF located using Blastx/COG3185.
  
 
 0.957
phhA
Phenylalanine 4-monooxygenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG3186; Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
  
 
 0.953
pheA
Chorismate mutase/prephenate dehydratase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1605.
    
 0.944
CV_0203
Probable 5-methyltetrahydrofolate-homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.923
CV_3407
Probable prephenate dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/COG0287.
    
 0.923
CV_0038
Probable histidinol-phosphate aminotransferase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0079.
   
 
 0.914
hisC
Histidinol-phosphate aminotransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0079; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
   
 
 0.914
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
     
 0.914
CV_2004
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1956.
    
  0.910
CV_2363
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/Blastx/COG1956.
    
  0.906
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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