Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
aesCarboxylesterase; Identified by sequence similarity; putative; ORF located using Blastx/COG0657. (268 aa)    
Predicted Functional Partners:
CV_3894
Probable purine-nucleoside phosphorylase; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.
 
  
 0.892
pqqL
Zinc protease; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0612; Belongs to the peptidase M16 family.
    
 
 0.823
CV_2033
Probable NADH-ubiquinone oxidoreductase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0702.
  
 
 0.821
nuoG
NADH-ubiquinone oxidoreductase, chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.
    
 
 0.820
nuoF
NADH-ubiquinone oxidoreductase, chain F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.
    
   0.801
nuoE
NADH-ubiquinone oxidoreductase, chain E; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1905.
    
   0.800
petC
Ubiquinol-cytochrome c reductase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2857/TC:3.D.3.2.1.
    
 
 0.800
nuoI
NADH-ubiquinone oxidoreductase, chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
   
 
 0.757
fdx1
Ferredoxin [4Fe-4S; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1145.
   
 
 0.757
CV_1543
Hypothetical protein.
   
 
 0.751
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.