Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CV_0379Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/COG1451. (165 aa)    
Predicted Functional Partners:
udk
Uridine kinase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0572.
    
  0.905
ushA
UDP-sugar diphosphatase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0737; Belongs to the 5'-nucleotidase family.
    
  0.901
CV_3083
Probable UDP-sugar diphosphatase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0737; Belongs to the 5'-nucleotidase family.
    
  0.901
CV_0124
Probable inhibitor of septum formation; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
     
  0.900
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
     
  0.900
nrdD
Ribonucleoside-triphosphate reductase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1328.
     
  0.900
pyrF
Orotidine 5`-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
     
  0.900
nagD
N-acetylglucosamine metabolism protein; Identified by sequence similarity; putative; ORF located using Blastx/COG0647; Belongs to the HAD-like hydrolase superfamily.
     
  0.900
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
     
  0.900
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
  0.900
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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