Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
speBAgmatinase; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily. (322 aa)    
Predicted Functional Partners:
speE
Conserved hypothetical protein; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
  
 
 0.956
CV_2025
Probable aminotransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0161.
  
 
  0.949
speA
Arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine.
  
 
 0.940
CV_3258
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG2957; Belongs to the agmatine deiminase family.
    
 0.918
adi
Arginine decarboxylase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1982.
    
 0.918
hutH
Histidine ammonia-lyase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2986; Belongs to the PAL/histidase family.
  
  
 0.778
leuS
leucyl-tRNA synthetase; Identified by sequence similarity; putative; ORF located using Blastx/COG0495; Belongs to the class-I aminoacyl-tRNA synthetase family.
    
   0.709
aruC
Acetylornithine transaminase; Identified by sequence similarity; putative; ORF located using Glimmer/Blastx/COG0160; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
  
 
 0.634
hutI
Imidazolonepropionase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1228; Belongs to the metallo-dependent hydrolases superfamily. HutI family.
  
  
 0.620
fadB
3-hydroxyacyl-CoA dehydrogenase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1024.
    
 0.606
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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