Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
CV_0499Probable 5-formyltetrahydrofolate cyclo-ligase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0212; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (203 aa)    
Predicted Functional Partners:
folD
Methylenetetrahydrofolate dehydrogenase/cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
 
  
 0.941
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
  
 
 0.927
CV_0500
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG3326.
       0.773
CV_0498
Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
     
 0.608
glyQ
glycyl-tRNA synthetase, alpha chain; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0752.
   
    0.463
cobU
Bifunctional adenosylcobalamin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.
       0.462
CV_0494
Probable outer membrane receptor protein; Identified by sequence similarity; putative; ORF located using Blastx/COG1629/TC:1.B.14.3.1.
       0.459
CV_0496
Probable substrate-binding periplasmatic (PBP) ABC transporter protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0614.
       0.452
pheT
phenylalanyl-tRNA synthetase beta chain; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0073; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.449
CV_0497
Hypothetical protein.
       0.431
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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