Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
holADNA-directed DNA polymerase, delta subunit; Identified by sequence similarity; putative; ORF located using Blastx/COG1466. (313 aa)    
Predicted Functional Partners:
holC
DNA polymerase III, chi subunit; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2927.
  
 
 0.998
holB
DNA-directed DNA polymerase III, delta subunit; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0470.
  
 
 0.996
dnaN
DNA-directed DNA polymerase, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for init [...]
 
 
 0.993
dnaE
DNA-directed DNA polymerase III, alpha subunit; Identified by sequence similarity; putative; ORF located using Blastx.
  
 0.991
dnaX
DNA polymerase subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 0.990
dnaQ
DNA-directed DNA polymerase, epsilon chain; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
    
 0.971
CV_2751
Probable exonuclease; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0847.
    
 0.971
CV_1020
Probable DNA-directed DNA polymerase III (epsilon subunit); Identified by sequence similarity; putative; ORF located using Blastx/COG0847.
   
 0.958
CV_2946
Probable DNA polymerase III; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0847.
    
 0.941
rlpB
Rare lipoprotein B precursor; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane; Belongs to the LptE lipoprotein family.
 
    0.787
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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