Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CV_0739Probable esterase; Serine hydrolase involved in the detoxification of formaldehyde. (279 aa)    
Predicted Functional Partners:
adhC
Alcohol dehydrogenase class III; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1062; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 0.999
fdnG
Formate dehydrogenase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0243/TC:5.A.3.2.1.
    
  0.901
fdoH
Formate dehydrogenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0437/TC:5.A.3.2.1.
     
  0.900
fdoI
Formate dehydrogenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2864/TC:5.A.3.2.1.
     
  0.900
CV_3496
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/COG1937.
 
  
 0.849
CV_3642
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/COG1937.
  
  
 0.760
lipA
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
 
      0.699
purU
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
  
  
 0.568
CV_0741
Probable transcriptional regulator, LysR family; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0583; Belongs to the LysR transcriptional regulatory family.
       0.540
CV_3039
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx.
  
     0.526
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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