STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
emrRTranscriptional repressor emr operon, MarR family; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1846. (166 aa)    
Predicted Functional Partners:
emrA
Multidrug resistance secretion protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1566/TC:8.A.1.1.1.
 
  
 0.885
CV_0766
Probable multidrug resistance protein; Identified by sequence similarity; putative; ORF located using Blastx/COG0477/TC:2.A.1.3.2; Belongs to the major facilitator superfamily.
 
   
 0.802
CV_0768
Probable outer membrane multidrug resistance lipoprotein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1538.
     
 0.795
CV_3905
Probable transcriptional regulator, MarR family; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1846.
  
   
 0.705
topA
DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]
     
 0.622
CV_0771
Probable MFS transporter; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0477/TC:2.A.1.2.7.
 
   
 0.558
CV_1769
Probable resistance protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0477/TC:2.A.1.11.1.
      
 0.527
CV_3014
Probable transmembrane transport protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0477.
      
 0.527
CV_0770
Probable arsenate reductase (glutaredoxin); Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1393.
  
    0.450
parC
DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
  
 0.441
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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