STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBKetohexokinase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2334; Belongs to the pseudomonas-type ThrB family. (313 aa)    
Predicted Functional Partners:
metL
Homoserine dehydrogenase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0460.
 
  
 0.934
thrC
Threonine synthase; Identified by sequence similarity; putative; ORF located using Blastx/COG0498.
    
 0.930
CV_0777
Hypothetical protein.
  
    0.893
ilvE
Branched-chain-amino-acid transaminase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
     
 0.821
CV_0203
Probable 5-methyltetrahydrofolate-homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.820
metY
O-acetylhomoserine (thiol)-lyase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2873.
    
  0.815
cysB2
Cystathionine beta-synthase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0517.
    
  0.813
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
  0.803
metE
5-methyltetrahydropteroyltriglutamate- homocysteine S-methyl; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
     
 0.802
cysE
Serine O-acetyltransferase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1045.
     
  0.800
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.