STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fsrFosmidomycin resistance protein, MFS family; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0477/TC:2.A.1.35.1. (399 aa)    
Predicted Functional Partners:
ispD
4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
  
   
 0.717
narG
Respiratory nitrate reductase alpha chain; Identified by sequence similarity; putative; ORF located using Blastx/COG0243; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
  
 0.691
ispF
2-C-methyl-d-erythritol-2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
   
  
 0.681
ispG
Conserved hypothetical protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
      
 0.681
CV_0799
Probable transcriptional regulator, AraC/XylS family; Identified by sequence similarity; putative; ORF located using Blastx/COG2207.
 
     0.665
cobA2
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
  
  
 0.661
narH
Nitrate reductase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1140.
  
  
 0.596
narJ
Nitrate reductase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2180.
  
  
 0.592
narI
Nitrate reductase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG2181/TC:5.A.3.1.1.
  
  
 0.583
rmlB
dTDPglucose 4,6-dehydratase; Identified by sequence similarity; putative; ORF located using Blastx/COG1088; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
      0.566
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.