Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mrcAPeptidoglycan glycosyltransferase; Identified by sequence similarity; putative; ORF located using Glimmer/Blastx/COG0744. (787 aa)    
Predicted Functional Partners:
ftsI
Penicillin-binding protein 3 precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
 
 
 0.974
dacC
D-ala-D-ala-carboxypeptidase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1686; Belongs to the peptidase S11 family.
     
 0.961
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
 
 
0.961
mtgA
Peptidoglycan glycosyltransferase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.
 
 
0.954
pbpB
Penicillin-binding protein 2; Identified by sequence similarity; putative; ORF located using Glimmer/Blastx/COG0744.
  
  
0.927
dacB
Serine-type D-Ala-D-Ala carboxypeptidase; Identified by sequence similarity; putative; ORF located using Blastx/COG2027.
     
 0.924
CV_0653
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG3107.
    
 
 0.789
mrdB
Probable rod shape-determining; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
  
   
 0.774
murC
UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
   
 0.746
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
  
   
 0.723
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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