Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
tpxThiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. (165 aa)    
Predicted Functional Partners:
sodB2
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.820
sodB1
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.756
minE
Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
   
    0.683
CV_2565
Probable oxidoreductase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1028; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
    0.682
fur
Ferric uptake regulation protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0735; Belongs to the Fur family.
   
  
 0.625
CV_0869
Hypothetical protein.
       0.560
trxB
Thioredoxin reductase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0492.
  
  
 0.492
clpX
ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
  
  
 0.486
glnS
glutaminyl-tRNA synthetase; Identified by sequence similarity; putative; ORF located using Blastx/COG0008.
  
    0.479
lepB
Signal peptidase I; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0681; Belongs to the peptidase S26 family.
   
    0.463
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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