STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hmgAHomogentisate 1,2-dioxygenase; Identified by sequence similarity; putative; ORF located using Blastx/COG3508. (377 aa)    
Predicted Functional Partners:
hpd
4-hydroxyphenylpyruvate dioxygenase; Identified by sequence similarity; putative; ORF located using Blastx/COG3185.
 
 0.999
CV_0972
Probable glutathione transferase zeta 1; Identified by sequence similarity; putative; ORF located using Blastx/COG0625.
 
 
 0.987
CV_0971
Probable fumarylacetoacetate hydrolase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0179.
 
  
 0.968
phhA
Phenylalanine 4-monooxygenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG3186; Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
 
  
 0.957
CV_2788
Probable isomerase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0179.
  
  
 0.817
CV_2366
Probable pterin-4-alpha-carbinolamine dehydratase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2154.
  
  
 0.673
groEL1
Chaperonin 60kD subunit; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
      
 0.640
efp
Elongation factor EF-P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
   
  
 0.555
tyrB2
Aromatic-amino-acid transaminase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1448.
  
  
 0.483
tyrB1
Aromatic-amino-acid transaminase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1448.
  
  
 0.483
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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