Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
trxCThioredoxin 2; Identified by sequence similarity; putative; ORF located using Glimmer/Blastx/COG0526; Belongs to the thioredoxin family. (139 aa)    
Predicted Functional Partners:
trxB
Thioredoxin reductase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0492.
 
 
 0.940
nrdA
Ribonucleoside-diphosphate reductase system; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 
 0.852
CV_2036
Probable peroxiredoxin/glutaredoxin family protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0695.
  
 
 0.815
lpdA1
Dihydrolipoamide dehydrogenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1249.
  
 
 0.800
groEL
Chaperonin 60kD subunit; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 
 0.790
groEL1
Chaperonin 60kD subunit; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 
 0.790
fusA
Elongation factor; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
   
 
 0.762
arsC
Arsenate reductase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0394; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
 
 0.755
nrdE
Ribonucleotide reductase system; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
 
 0.754
CV_3140
Probable protein-tyrosine-phosphatase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0394; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
 
 0.735
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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