Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
folEGTP cyclohydrolase I protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0302. (206 aa)    
Predicted Functional Partners:
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0801.
 
  
 0.969
folP
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
  
 0.958
CV_3508
Probable 6-pyruvoyltetrahydrobiopterin synthase; Identified by sequence similarity; putative; ORF located using Blastx/COG0720.
  
 
 0.957
folB
Dihydroneopterin aldolase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1539.
  
  
 0.955
ribAB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
  
 
 0.938
mtrA
GTP cyclohydrolase I; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0302.
  
  
 
0.927
ribA
GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.
   
 
 0.923
phoD
Identified by sequence similarity; putative; ORF located using Glimmer/Blastx/COG3540.
    
 0.923
ntpA
ATP diphosphatase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0494.
  
 
 0.912
moaA2
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
    
 0.909
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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