STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepNIdentified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0308. (872 aa)    
Predicted Functional Partners:
pepA
Aminopeptidase A/I; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
  
 0.977
pepD
Aminoacyl-histidine dipeptidase precursor; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2195.
     
 0.928
gshB
Glutathione synthetase protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0189.
    
 0.926
CV_4276
Probable glutamate-cysteine ligase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx.
   
 
 0.918
ggt
G-glutamyltransferase precursor; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0405.
     
 0.903
CV_2904
Conserved hypothetical protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
     
  0.900
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.873
cysK
Cysteine synthase; Identified by sequence similarity; putative; ORF located using Blastx/COG0031; Belongs to the cysteine synthase/cystathionine beta- synthase family.
   
 0.824
CV_3394
Probable cystathionine gamma-lyase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0626.
  
 
 0.813
CV_3597
Probable cysteine synthase B; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0031.
    
 0.807
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.